Here you can find scientific publications.

Future IOL Technologies

December 2020
Some IOL innovations will have a positive impact way beyond cataract surgery like the lens/sensor that is going to benefit the not so small number of patients who suffer simultaneously from cataract and glaucoma.
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Intraocular Pressure Telemetry for Managing Glaucoma During the COVID-19 Pandemic

December 2020
IOP measurements acquired by the patients during the lockdown period were collected by physicians who were located remotely.
A questionnaire was sent to 10 participating study centers to evaluate the clinical impact of remote monitoring of IOP via the IOP sensor system.

The results show the feasibility of patient acquired measurement of IOP in conjunction with remote IOP monitoring by physicians as feasible with an implantable sensor.
The data obtained had an impact on clinical decision-making, including adjustment of ocular hypotensive therapy and avoiding unnecessary office visits during the COVID-19 pandemic.
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Influence of electromagnetic radiation emitted by daily-use electronic devices on the Eyemate® system in-vitro: a feasibility study

September 2020
Background: Eyemate® is a system for the continual monitoring of intraocular pressure (IOP), composed of an intraocular sensor, and a hand-held reader device. As the eyemate®-IO sensor communicates with the hand-held reader telemetrically, some patients might fear that the electronic devices that they use on a daily basis might somehow interfere with this communication, leading to unreliable measurements of IOP….
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Use of a novel telemetric sensor to study interactions of intraocular pressure and ganglion-cell function in glaucoma  

July 2020
Telemetric implantable micro-sensor for measurement of intraocular pressure enables studying interaction of intraocular pressure and ganglion cell function, providing better understanding of intraocular pressure variations and its impact on visual field loss in glaucoma patients.
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Short-Term and Long-Term Variability of Intraocular Pressure measured with an Intraocular Telemetry Sensor in Patients with Glaucoma

July 2020
Continual IOP monitoring shows that IOP has moderate short-term and high long-term variability in glaucoma patients. These findings demonstrate that single IOP measurements do not characterize day to day variations in IOP. Moreover, they show the importance of continual IOP monitoring in glaucoma patients. 
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Using sensors to estimate intraocular pressure: a review of intraocular pressure telemetry in clinical practice

July 2020
With regards to the intraocular Eyemate monitor, its implantable nature reserves it for patients in more advanced stages of the disease. Less of a diagnostic test and more of monitoring tool, it is clear that simple and accurate self- monitoring of IOP has a strong potential to improve the care and follow-up of glaucoma patients…
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Weekly and seasonal changes of intraocular pressure measured with an implanted intraocular telemetry sensor

June 2020
Conclusion This study confirms previously observed seasonal variations of IOP. IOP was significantly higher in winter compared with summer months. Moreover, IOP was lower on Friday than on other days. The explanation for these results …..
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Device profile of the EYEMATE-IO™ system for intraocular pressure monitoring: overview of its safety and efficacy

May 2020
„….In summary, the results of two independent prospective studies on the Eyemate-IO™ could show a promising potential for telemetric IOP measurement. …“
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The Value of Intraocular Pressure Telemetry in Monitoring the Therapeutic Effect of Glaucoma Medications

March 2020
„….eyemate paves the way for personalized glaucoma care, in which the actual effect of lifestyle and treatments can be self-monitored by the patients and therapeutic decisions can be made accordingly in real time before there is further optic nerve injury….“
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Influence of electromagnetic radiation emitted by daily-use electronic devices on the Eyemate® System.

November 2019
Conclusion: Measurements made by the eyemate® system showed no apparent signal drift or evidence of being influenced by external electromagnetic radiation produced by the devices that we tested. Patients who already have the eyemate®-IO sensor implanted, and those who are considering to have one, should be informed that the electromagnetic radiation emitted by their daily-use electronic devices does not interfere with IOP measurements made by the eyemate® system.
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Telemetric measurement of intraocular pressure via an implantable pressure sensor – twelve-month results from the ARGOS-02 trial.

September 2019
The aim of this study was to investigate the safety and performance of the second generation of an implantable intraocular pressure (IOP) sensor in patients with primary open angle glaucoma (POAG).
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Influence of physiological Parameters on IOP during physical activity - a Pilot study with the EYEMATE-IO™

June 2019
Accurate measurements of intraocular pressure by clinically available methods is typically limited to static situations in standard body positions. The aim of this pilot study was to employ a novel telemetric intraocular pressure sensor (EYEMATE-IO™, Implandata Ophthalmic Products GmbH, Hannover, Germany)for recording IOP during different body positions and physical activities.
Correlation between blood pressure, intraocular pressure and intracranial pressure – a pilot study

June 2019
To simultaneously measure intraocular pressure (IOP), intracranial pressure (ICP) and blood pressure (BP) variations in glaucoma patients previously provided with an implantable intraocular sensor (EYEMATE-IOTM), while inducing controlled
orthostatic pressure variations with the use of a tilt table.
Effect of gaze direction and lid squeezing on intraocular pressure in glaucoma patients using a novel implantable intraocular sensor

June 2019
Quantification of immediate intraocular pressure (‘IOP’) changes in response to voluntary eye globe movement and lid squeezing
Telemetric Intraocular Pressure Monitoring after Boston Keratoprosthesis surgery with the Eyemate-IO Sensor: Dynamics in the first year

February 2019 / June 2019
To analyse the dynamics of telemetrically measured intraocular pressure (IOP) during year one after implantation of a Boston Keratoprosthesis Type I (BI-KPro) and to compare agreement of telemetric IOP measurements with finger palpation
Miniaturization in Glaucoma Monitoring and Treatment: A Review of New Technologies That Require a Minimal Surgical Approach

February 2019
This review focuses on the Eyemate (Argos) intraocular sensor, which offers a new way to reliably measure 24 h IOP, and on intraocular sustained release systems for pharmacological glaucoma therapy.
Automated, Noncontact Intraocular Pressure Home Monitoring after Implantation of a Novel Telemetric Intraocular Pressure Sensor in Patients with Glaucoma: A Feasibility Study

December 2018
Purpose. Reliable and regular assessment of intraocular pressure (IOP) is important for the monitoring of patients with glaucoma. The purpose of this study was to evaluate the feasibility of a novel system for the automated, noncontact measurement of IOP.
Potential Savings from Visit Reduction of Continuous Intraocular Pressure Monitoring

December 2018
1Jiaxi Dong, 2Zeba A Syed; 1Kenneth Fan; 1Ali F Yahya; 1,2Samir A Melki
Telemetric Intraocular Pressure Monitoring after Boston Keratoprosthesis Surgery

October 2018
Telemetric Intraocular Pressure Monitoring after Boston Keratoprosthesis Surgery
Implantation and testing of a novel episcleral pressure transducer: A new approach to telemetric intraocular pressure monitoring

January 2018
Measurement of intraocular pressure (IOP) is an essential tool in monitoring glaucoma. Single IOP assessments during clinical routine examinations represent punctual values and are not able to identify IOP fluctuations and spikes….
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Long-term follow-up after implantation of a telemetric intraocular pressure sensor in patients with glaucoma: a safety report

November 2017
Long-term follow-up after implantation of a telemetric intraocular pressure sensor in patients with glaucoma: a safety report

Antonis Koutsonas MD, Peter Walter MD, Gernot Roessler MD and Niklas Plange MD Department of Ophthalmology, RWTH Aachen University, Aachen, Germany Correspondence: Dr Antonis Koutsonas, Dept. of Ophthalmology, RWTH Aachen
University, Pauwelsstr. 30, 52074 Aachen, Germany

Short running title: Long-term ocular pressure sensor follow-up
Received 30 May 2017; accepted 7 November 2017
Conflict of interest: None Funding sources: Financial support of the original 1-year study was provided by
Implandata Ophthalmic Products GmbH, Hannover, Germany
Investigation of a novel implantable suprachoroidal pressure transducer for telemetric intraocular pressure monitoring*

June 2017
Intraocular Pressure (IOP) is an important and modifiable risk factor for glaucoma progression.

IOP fluctuations and spikes often remain undetected despite clinical routine examinations.

Selbsttonometrie mit einem telemetrischen, intraokularen Drucksensor bei Patienten mit Glaukom

August 2015
Institut: Klinik für Augenheilkunde, Uniklinik RWTH Aachen / Autoren: Dr. A. Koutsonas, Prof. P.Walter, Prof. N. Plange

Implantation of a Novel Telemetric Intraocular Pressure Sensor in Patients With Glaucoma (ARGOS Study): 1-Year Results

February 2015
Antonis Koutsonas, Peter Walter, Gernot Roessler, and Niklas Plange
Department of Ophthalmology, RWTH Aachen University, Aachen, German
An Implantable Intraocular Pressure TransducerInitial Safety Outcomes

June 2014
Original Investigation
Samir Melki, MD, PhD; Amit Todani, MD; George Cherfan, MD
An overview of home tonometry and telemetry for intraocular pressure monitoring in humans

June 2014
Edward Yung & Valerie Trubnik & L. Jay Katz

Received: 16 November 2013 /Revised: 29 April 2014 /Accepted: 6 May 2014 /Published online: 29 May 2014 # Springer-Verlag Berlin Heidelberg 2014
Reliable intraocular pressure measurement using automated radio-wave telemetry”, Eleftherios I. Paschalis

January 2014
Intraocular Pressure Measurement by Radio Wave Telemetry

August 2011

Amit Todani, et al


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